Page 128 - The Indian Optician Digital Edition March-April 2024
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ANTI-VEGF






          INJECTIONS:





          REVOLUTIONISING RETINAL CARE















                                                   he diagnosis of a vision-threatening retinal disease

                 SANJAY K MISHRA                   can be disturbing. However, Anti-VEGF injections
                                              Tare the game-changers for patients suffering
                                              from age-related macular degeneration (AMD) and
            THIS ARTICLE WAS JOINTLY          diabetic macular edema (DME), offering new hope
            COMPILED BY                       for preserving vision (figures 1-6). Unlike traditional
            SANJAY K. MISHRA,                 treatments that may address symptoms but not the
            Scientist, Dr. R. P. Centre for   underlying cause, anti-VEGF therapy offers a targeted
            Ophthalmic Sciences, All India    approach, directly attacking the root of the problem.
            Institute of Medical Sciences
            (AIIMS), New Delhi                UNDERSTANDING THE VILLIAN: VEGF AND ITS
            MAJ. GEN. (DR.) TEJINDER S.       DESTRUCTIVE INFLUENCE
            AHLUWALIA,
            Professor and Head of Department     At the core of many retinal diseases lies a villianous
            of Ophthalmology, NIMS University   protein called vascular endothelial growth factor
            Rajasthan, Jaipur                 (VEGF). VEGF plays a crucial role in healthy blood
                                              vessel growth, but in the eye, its overactivity becomes
            DR. ROHAN CHAWLA,
            Additional Professor of           destructive. Uncontrolled VEGF production triggers the
            Ophthalmology, Dr. R. P. Centre   formation of abnormal new blood vessels in the retina.
            for Ophthalmic Sciences, All India   These abnormal vessels are weak and leaky, causing
            Institute of Medical Sciences     fluid to accumulate and badly affect the retina's
            (AIIMS), New Delhi
                                              function. This results in blurring of vision, distortion
            SURESH K. YADAV, Scientist,       (metamorphopsia), and sometimes, complete loss of
            Dr R P Centre for Ophthalmic      vision if not managed well.
            Sciences, AIIMS, New Delhi
                                              HOW CAN ANTI-VEGF INJECTIONS SPOIL THE
            RAJESH KUMAR, Senior              VILLIAN'S PLOT?
            Optometrist, PGIMS, University of
            Health Sciences, Rohtak, Haryana
                                                 Anti-VEGF injections act as highly trained assassins
            BHAWANI SINGH MEENA               targeting the villianous VEGF. These injections
            Scientist, Dr. R. P. Centre for   contain specialised drugs that bind to VEGF receptors,
            Ophthalmic Sciences, All India    essentially blocking VEGF's ability to wreak havoc.
            Institute of Medical Sciences
            (AIIMS), New Delhi                By neutralising VEGF's influence, anti-VEGF therapy
                                              achieves several critical goals:


      124 | THE INDIAN OPTICIAN | MAR-APR 2024                                                             CLINICAL
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